Recent Lab News:
11/17/21- Yudong Gao receives a prestigious Brain and Behavior Research Foundation Young Investigator award.
11/17/21- New paper, by lead author Dr. Eda Erata, describes a new molecular mechanism of Epilepsy-Aphasia following
loss of the synaptic scaffolding protein Cnksr2.
07/16/21- Our newest paper, led by Dr. Shataakshi O’Neil, using iBioID to discover presynaptic proteomes and uncover a new
molecular mechanism of short-term plasticity, is published!
07/12/21- Shataakshi Dube O’Neil becomes the newest member of the lab to earn her PhD.
04/15/21- Lab is very proud of Jamie Courtland and Tyler Bradshaw for successfully defending their PhDs in Neurobiology!
 03/22/21- eLife paper using mouse genetics and spatial proteomics to tease out how mutations in WASHC4 lead to cognitive
and movement disorders.
11/11/20- Nature paper using new surface Split-TurboID method to discover how astrocytes regulate inhibitory synapses.
7/06/20- Paper in Cell Reports linking altered synaptic cytoskeleton to neural circuit pathology driving social dysfunction.
1/03/20- Akiyoshi Uezu publishes new paper in Elife: “Essential Role of InSyn1 in dystroglycan complex integrity and
cognitive behaviors in mice”.
11/15/19- “Plug and Play Protein Modification using HiUGE” is selected as one of ten top papers in Neuron for 2019!
7/01/19- Yudong Gao publishes new paper in Neuron: “Plug and Play Protein Modification using HiUGE      

Neural development of synapses and their ability to tune their strengths of connections in response to experience are essential for our ability to think, remember, express emotion, etc.  Abnormalities of these synaptic connections contribute to Intellectual Disability, Autism, Alzheimer's Disease, Epilepsy, and Schizophrenia.  We are discovering the inner components of these synapses and the cellular mechanisms underlying these disorders.  Postdoctoral applicants with experience in proteomics, protein engineering, computational biology, 2P-FLIM imaging, or electrophysiology are especially encouraged to apply.