Scott H. Soderling, Ph.D.: Dr. Soderling received his Ph.D. in Pharmacology at the Univ. of Washington. As an HHMI postdoctoral fellow he uncovered a new neuronal cytoskeletal signaling complex implicated in intellectual disability that facilitates synaptogenesis. He was recruited to Duke University in 2005. Dr. Soderling also serves as the Director of Graduate Studies for Cell Biology and the Scientific Director of the Duke Mouse Transgenic Facility.
Il Hwan Kim, Ph.D.: Dr. Kim received his Ph.D. at Korea University in Seoul. He has pioneered several new areas in the lab, including a new model of postnatal hydrocephalus associated with abnormal neuronal progenitor migration. Dr. Kim recently discovered the role of Arp2/3 regulation of dendritic spine plasticity and maintenance in vivo. He found this pathway in the forebrain is implicated in schizophrenia-related disorders. He is currently following up on this to decipher the circuitry underlying these abnormalities.
Akiyoshi Uezu, M.D., Ph.D.: Dr. Uezu received his MD/Ph.D at Kumamoto University in Japan. Since joining the lab Dr. Uezu has pioneered the development of new proteomic approaches. He has used these novel methods to identify the molecular complexes that mediate synaptic inhibition in vivo.
Jamie Croucher, B.S. Biology (Haverford College): Jamie joined our lab in 2017 as part of the Medical Scientist Training Program of Duke Medical School. Jamie is interested in merging the biological mechanisms of neurodevelopmental disorders with her medical school training. She is studying the molecular mechanisms that regulate inhibitory neuronal populations that are highly implicated in psychiatric disorders.
Yudong Gao, Ph.D.: Dr. Gao obtained his Ph.D. from the University of Tennessee Memphis and joined the lab in 2016. Dr. Gao studies the molecular mechanisms of plasticity at inhibitory synapses.
Erin Spence, B.S. Biology, B.A. Psychology (UNC): Erin joined our laboratory in the summer of 2013. She entered Duke through the Cell & Molecular Biology Program and was awarded an NIH Predoctoral Fellowship in 2015. Erin is working on mechanisms of early synaptogenesis. She uses a combination of ex vivo imaging, proteomics, and CRISPR-genome editing to understand how the actin cytoskeleton guides early excitatory synapse formation in the first weeks of life.
Tyler Bradshaw, B.S. Cell & Molecular Biology, (University of Washington): Tyler previously worked in our laboratory as a research technician before joining on as a graduate student through the Duke Neurobiology program. As a technician, Tyler worked with Aki to develop a proteomic approach to identity inhibitory synaptic proteins. As a graduate student he following up on this study by developing high-throughput functional screens to quantify mechanisms of inhibition relevant to epilepsy.
Shataakshi Dube, B.S. Biology, (Butler University): Shataakshi joined the lab in 2016 through the Neurobiology program. She was recently awarded a fellowship to attend the Cold Spring Harbor course on Ion Channels and Synaptic Transmission and is now studying how actin remodeling modulates presynaptic properties.
Patrick Devlin, B.S. Biology, (Davidson University): Patrick helps manage the lab mouse colony, which is no small task given we have almost 30 lines of mice! He also works with Dr. Akiyoshi on projects related to new proteomic approaches to quantify in vivo synaptic complexes.