contact us

Use the form on the right to contact us.

You can edit the text in this area, and change where the contact form on the right submits to, by entering edit mode using the modes on the bottom right.

307 Research Dr
Durham, NC, 27705
United States

signphoto4.jpg

Lab Members

Scott Soderling  Professor., PI.

Scott Soderling
Professor., PI.

Scott H. Soderling, Ph.D.:  Dr. Soderling received his Ph.D. in Pharmacology at the Univ. of Washington.  As an HHMI postdoctoral fellow he uncovered a new neuronal cytoskeletal signaling complex implicated in intellectual disability that facilitates synaptogenesis.  He was recruited to Duke University in 2005.  Dr. Soderling serves as the Chair of Cell Biology and is the Scientific Director of the Duke Mouse Transgenic Facility.

 

 

 

 

 

Akiyoshi Uezu  Postdoctoral Fellow

Akiyoshi Uezu
Postdoctoral Fellow

Jamie Courtland  MD/PhD student

Jamie Courtland
MD/PhD student

Yudong Gao  Postdoctoral Fellow

Yudong Gao
Postdoctoral Fellow

Akiyoshi Uezu, M.D., Ph.D.: Dr. Uezu received his MD/Ph.D at Kumamoto University in Japan. Since joining the lab Dr. Uezu has pioneered the development of new proteomic approaches.  He has used these novel methods to identify the molecular complexes that mediate synaptic inhibition in vivo. 

 

 

 

 

 

Jamie Courtland, B.S. Biology (Haverford College): Jamie joined our lab in 2017 as part of the Medical Scientist Training Program of Duke Medical School. Jamie is interested in merging the biological mechanisms of neurodevelopmental disorders with her medical school training.  She is studying the molecular mechanisms that regulate inhibitory neuronal populations that are highly implicated in psychiatric disorders.

 

Yudong Gao, Ph.D.: Dr. Gao obtained his Ph.D. from the University of Tennessee Memphis and joined the lab in 2016.  Dr. Gao studies the molecular mechanisms of plasticity at inhibitory synapses.

Erin Hisey  Postdoctoral Fellow

Erin Hisey
Postdoctoral Fellow

Erin Hisey, Ph.D. Neuroscience (Duke University). Dr. Hisey joined our lab in 2018. She is working to understand the underlying synaptic to neural circuit basis for cognitive deficits in several mouse models of intellectual disability. 

Tyler Bradshaw  Graduate Student

Tyler Bradshaw
Graduate Student

Shataakshi Dube  Graduate Student

Shataakshi Dube
Graduate Student

Julie Kent  Lab Manager

Julie Kent
Lab Manager

Tyler BradshawB.S. Cell & Molecular Biology (University of Washington): Tyler previously worked in our laboratory as a research technician before joining on as a graduate student through the Duke Neurobiology program.  As a technician, Tyler worked with Aki to develop a proteomic approach to identity inhibitory synaptic proteins.  As a graduate student he following up on this study by developing high-throughput functional screens to quantify mechanisms of inhibition relevant to epilepsy. 

 

Shataakshi DubeB.S. Biology (Butler University): Shataakshi joined the lab in 2016 through the Neurobiology program.  She recently attended the Cold Spring Harbor course on Ion Channels and Synaptic Transmission and is now studying how actin remodeling modulates presynaptic properties.

 

Julie KentB.S. Zoology (Michigan State University): Julie is our lab manager and keeps us happy and organized with a well-running laboratory. Using her expertise in animal husbandry and transgenic mouse technologies, she is also spearheading novel ideas and experiments for new transgenics to uncover the molecular landscape of neuronal cell interactions.

Tetsuya Takano  Postdoctoral Fellow

Tetsuya Takano
Postdoctoral Fellow

Eda Erata  Graduate Student

Eda Erata
Graduate Student

Alicia Purkey   Postdoctoral Fellow

Alicia Purkey

Postdoctoral Fellow

Kazi Hossain   Graduate Student

Kazi Hossain

Graduate Student

Walter "Evan" Brown  Research Technician

Walter "Evan" Brown
Research Technician

John Wallace  Research Technician

John Wallace
Research Technician

Tetsuya Takano, Ph.D.: Tetsuya received his PhD from Tokyo Metropolitan University.  Dr. Takano is developing a novel in vivo BioID proteomic approach to investigate novel mechanisms of synaptic modulation in mice. 

 
 
 
 

Eda Erata, B.S. Molecular Biology & Genetics (Sabanci University, Istanbul, Turkey): Eda joined our lab through the Duke PhD program in Cell and Molecular Biology.  She is using CRISPR-genome editing and in vivo BioID to tackle endogenous synaptic proteomes linked to Autism Spectrum Disorders.   

 

Alicia Purkey, Ph.D. Alicia obtained her Ph.D. from the University of Colorado Anschutz Medical Campus, and then joined the Soderling lab in June 2019. Alicia’s background in synaptic physiology, super resolution imaging as well as an in-depth understanding of synaptic protein function are invaluable assets as the lab continues to unravel the molecular mechanisms of inhibitory synapse function. Alicia’s work focuses on how the localization and function of kinases found at inhibitory synapses regulate synaptic transmission and organization through phosphorylation.

Kazi Hossain, B.S. Biology (City College of New York, CUNY): Kazi joined the lab in 2019 through Duke’s Developmental and Stem Cell Biology (DSCB). He is interested in the link between genetic mutations and behavior abnormalities at the level of neural circuit alterations.

 

Evan Brown, B.S. Chemistry (UNC-Asheville): Evan uses his expertise in molecular biology to assist the lab in generating and evaluating various novel CRISPR-based approaches for understanding how synaptic molecules function in vivo.

 

 
 

John Wallace, B.S. Biology and Psychology (James Madison University): John works with Tetsuya to develop and utilize innovative in vivo proteomic and genome editing approaches to reveal molecular mechanisms that drive the neuronal synaptic functions of astrocytes.